Situated atop a hillock in Manjanikkara, near Omallur, Pathanamthitta District in South Kerala, this monastery was established by late Mor Yulius Elias Qoro, Patriarchal delegate to Malankara. On February 13th, 1932, the late Patriarch Mor Ignatius Elias III entered eternal rest and his remains are interred at the monastery. (In the photographs of the exterior above, the tomb of the late Patriarch is within the campanile like structure on the south side of the sanctuary.)

The remains of late Mor Yulius Elias Qoro and Mor Yulius Yacoub, former Patriarchal delegates to Malankara are also interred in this church.

The Manjanikkara Dayro is the seat of the Patriarchal Delegate to Malankara (currently, Mor Ostatheos Benyamin Joseph) and the metropolitan of the Simhasana churches (churches administered directly by the Patriarchate).